Better Treatment Demands Better Measurement
ABOUT
Neuroscience Meets Artificial Intelligence
In partnership with the most prestigious institutions in the world, SPARK Neuro enables a new era of analyzing brain activity to better understand diseases of the central nervous system.
VISION: A world where measuring and caring for brain health is universally accessible.
MISSION: To revolutionize brain measurement for better clinical care and therapeutic discovery through SPARK Neuro’s AI technology.
APPLICATIONS
More Objective Answers at the Earliest Stages
SPARK Neuro builds diagnostic and monitoring applications for more accurate and objective measurement of brain-based diseases.
Drug Development
SPARK’s Drug Development Dashboard provides early insights for clinical trials, saving time and money throughout the course of drug development. The Dashboard can increase the success of central nervous system (CNS) therapeutic trials through brain-based measures for:
Early signs of efficacy: De-risk future stage drug trials by measuring the earliest neurological signs of efficacy
Population stratification: Uncover distinct patient traits that predict drug response vs. non-response
Pharmacodynamics: Examine if the drug crosses the blood-brain barrier (BBB) and engages the intended target
Dosing: Identify the optimal dose range, including the minimum dose to produce a neural response
Clinical Care
SPARK Neuro is currently conducting clinical studies for the diagnosis and monitoring of:
Mild Cognitive Impairment (MCI) and Dementia
Alzheimer’s Disease
Dementia with Lewy Bodies
Parkinson’s Disease
Multiple System Atrophy
Frontotemporal Dementia
Normal Pressure Hydrocephalus
Brain Injuries
Mental health conditions, including Depression, Anxiety, PTSD, ADHD, and Schizophrenia
APPLICATIONS
More Objective Answers at the Earliest Stages
SPARK Neuro builds diagnostic and monitoring applications for more accurate and objective measurement of brain-based diseases.
SPARK’s Drug Development Dashboard provides early insights for clinical trials, saving time and money throughout the course of drug development. The Dashboard can increase the success of central nervous system (CNS) therapeutic trials through brain-based measures for:
- Early signs of efficacy: De-risk future stage drug trials by measuring the earliest neurological signs of efficacy
- Population stratification: Uncover distinct patient traits that predict drug response vs. non-response
- Pharmacodynamics: Examine if the drug crosses the blood-brain barrier (BBB) and engages the intended target
- Dosing: Identify the optimal dose range, including the minimum dose to produce a neural response
SPARK Neuro is currently conducting clinical studies for the diagnosis and monitoring of:
- Mild Cognitive Impairment (MCI) and Dementia
- Alzheimer’s Disease
- Dementia with Lewy Bodies
- Parkinson’s Disease
- Multiple System Atrophy
- Frontotemporal Dementia
- Normal Pressure Hydrocephalus
- Brain Injuries
- Mental health conditions, including Depression, Anxiety, PTSD, ADHD, and Schizophrenia
COLLABORATORS
Advanced Scientific Discovery
Mayo Clinic
SPARK Neuro’s formal collaboration, ongoing research efforts, and grant co-awards with Mayo Clinic are core to our methods for developing advanced diagnostic technology for neurological disorders.
US Government
SPARK’s ability to advance scientific discovery is underpinned by extensive National Institutes of Health (NIH) grants, Department of Defense (DoD) funding, US Army Medical awards, and US Air Force contracts.
Other Collaborators
We have numerous collaborations with prestigious clinical, research, and academic institutions, including Johns Hopkins, University of Oxford, Providence Health, Massachusetts Institute of Technology, and numerous neurology and psychiatry clinics.
PLATFORM
Advanced Technology
SPARK combines the power of neurological data with advanced machine learning to develop highly sensitive and specific measures of cognitive function and CNS diseases.
Electroencephalography (EEG)
EEG data is an incredibly rich signal, providing about 1 million observations of brain activity data per minute. However, the richness of that signal comes with complexity beyond what the human eye can see, limiting the ability to provide meaningful insights with traditional approaches.
Using FDA cleared EEGs, SPARK Neuro combines the power of modern cloud computing and advanced analytic techniques, enabling us to peer deeper into brain function.
Machine Learning Algorithms
Our platform’s artificial intelligence (AI) infrastructure unlocks the full potential of EEG by harnessing machine learning (ML) and advanced deep-learning techniques to decode this highly complex array of brain activity signals.
This approach allows us to develop algorithms for objective measurement of cognitive disorders and to provide clinical and pharmacological insights with superior diagnostic accuracy.
User Friendly Software
Our intuitive, end-to-end software guides experts and non-experts alike through a few simple steps, allowing any user the ability to run a SPARK Scan with the push of a button.
The software automatically transmits test results to the cloud where data is processed by our ML pipelines, returning an interactive report in seconds.
PLATFORM
Advanced Technology
SPARK combines the power of neurological data with advanced machine learning to develop highly sensitive and specific measures of cognitive function and CNS diseases.
Electroencephalo-
graphy (EEG)
EEG data is an incredibly rich signal, providing about 1 million observations of brain activity data per minute. However, the richness of that signal comes with complexity beyond what the human eye can see, limiting the ability to provide meaningful insights with traditional approaches.
Using FDA cleared EEGs, SPARK Neuro combines the power of modern cloud computing and advanced analytic techniques, enabling us to peer deeper into brain function.
Machine Learning
Algorithms
Our platform’s artificial intelligence (AI) infrastructure unlocks the full potential of EEG by harnessing machine learning (ML) and advanced deep-learning techniques to decode this highly complex array of brain activity signals.
This approach allows us to develop algorithms for objective measurement of cognitive disorders and to provide clinical and pharmacological insights with superior diagnostic accuracy.
User Friendly
Software
Our intuitive, end-to-end software guides experts and non-experts alike through a few simple steps, allowing any user the ability to run a SPARK Scan with the push of a button.
The software automatically transmits test results to the cloud where data is processed by our ML pipelines, returning an interactive report in seconds.
Contact Us
If you are a pharmaceutical professional, researcher, or clinician working with neurological or psychiatric disorders, please don’t hesitate to reach out.